New lead for in utero pacing for fetal congenital heart block

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Outcome of isolated congenital complete heart block diagnosed in utero.

OBJECTIVE To establish identifiable prenatal factors in fetal heart block which might predict death in utero, the need for intervention, or the probability of pacemaker requirement. SETTING Tertiary referral unit for fetal echocardiography. SUBJECTS 36 fetuses with congenital complete heart block and structurally normal hearts identified between 1980 and 1993. METHODS Maternal anti-Ro ant...

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Fetal Echo Doppler for Early Detection of Congenital Heart Block

Background: Fetal echo Doppler methods, detecting prolonged atrioventricular (AV) time intervals a mechanical PR interval corresponding to the electrical PR interval in ECG, have been proposed for surveillance of pregnancies at risk of complete congenital heart block (CCHB). The aim of this thesis was; to validate these Doppler methods by comparing AV time intervals from left ventricular inflow...

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A serologic marker for fetal risk of congenital heart block.

OBJECTIVE To analyze the humoral immune response to Ro/SSA and La/SSB antigens in detail, in order to identify markers in mothers at high risk of having children with congenital heart block (CHB). METHODS Serum samples were obtained from 9 Ro/La-positive mothers who gave birth to affected children, from their 8 newborns with CHB, and from 26 Ro/La-positive mothers whose children were healthy....

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Natural history of postoperative heart block in congenital heart disease: implications for pacing intervention.

After half a century of major progress in congenital heart disease management, atrioventricular conduction block continues to complicate 1-3% of surgical procedures. Unless treated with an implanted pacemaker, permanent postoperative heart block is associated with 28-100% mortality. Postoperative heart block often proves to be transient, typically resolving within 10 days of onset. The duration...

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Correlation of Maternal Autoantibodies with Fetal Congenital Heart Block.

BACKGROUND Autoimmune fetal congenital heart block (CHB) is the most severe manifestation of neonatal lupus, and it is seen when maternal autoimmune antibodies cross the placenta and damage the AV node of the fetus. CHB is mainly associated with maternal SLE with anti-Ro/SSA- and anti-La/SSB-positive status, and incidence of CHB increases when both the antibodies are present. This study was con...

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ژورنال

عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery

سال: 2003

ISSN: 0022-5223

DOI: 10.1016/s0022-5223(03)00220-4